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My subscription to Psychiatric Times always has something interesting associated with it. Bottom line: the stereotype of the crazy, isolated cat lady may be dead-on true.
Environmental Factors in Schizophrenia Three epidemiological studies bolster the evidence for infectious
and social influences on the development of schizophrenia. Swedish
national registers show an association between psychotic illness
and childhood viral, but not bacterial, infections of the central
nervous system (CNS). Dalman et al. (p.
59) analyzed hospitalizations
for CNS infections before age 13 and psychotic illnesses from
age 14 onward in children born during 1973–1985. Psychosis
risk was almost tripled by childhood mumps exposure and was
over 16 times as high after cytomegalovirus exposure. Using
blood samples collected routinely by the U.S. military, Niebuhr
et al. (p.
99) confirmed a relationship between schizophrenia
and
toxoplasmosis. IgG antibodies to
Toxoplasma gondii were
compared in service members medically discharged with schizophrenia
between 1992 and 2001 and matched healthy subjects. The antibody
level was nearly 25% higher for the subjects with schizophrenia
in the 6 months preceding the diagnosis or after it. Dr. Alan
Brown examines these two studies in an editorial on p.
7. Veling
et al. (p.
66) identified social isolation as a risk factor
for
psychotic disorders among immigrants in The Hague. City
records provided the ethnic backgrounds and locations of residents
who received a first diagnosis of psychotic disorder over 7
years. Immigrants in neighborhoods with high densities of immigrants
from the same country had a rate of psychotic illness similar
to that of native Dutch residents, but those in neighborhoods
with low densities of the same ethnic group had a rate more
than double that for the Dutch.